Freeze dry machine

Detailed operation sequence of the freeze dryer
1. Inspection before operation
1 Check if the circulating water pressure and compressed air pressure meet the requirements.
2 Check the oil level of the silicone oil, and the oil level and color of the vacuum pump are normal.
3 Check if the compressor oil level, Freon liquid level and moisture content display color are within the normal range.
4 Check if the computer program is normal.
5 Check that the values ​​of the pressure gauge and thermometer are within the normal range.
6 Check that all valves are closed.
2. Loading
1 Control the position operator to determine the program used on the control screen.
2 Start the procedure of the lyophilizer charging stage.
3 Observe the freeze-drying curve and the operation diagram of the equipment, and refer to the reference.
4 When the temperature on the graph drops to 0 °C, notify the sterile room.
3. Start
After the clean room is closed, the operator of the control position will start the freeze-drying procedure immediately after receiving the notice.
4. Run
1 Note that the freeze-drying curve is consistent with the set curve.
2 Observe whether the equipment control system, vacuum system, heating system and refrigeration system are normal.
3 Observe whether the various components and each door reading action are correct during the operation in each stage.
4 The meter should be accurate and the equipment should operate without abnormal noise.
5 Observe that each oil level and liquid level should meet the requirements, and the moisture content of the refrigerant should be within the specified range.
5. Shutdown
When the drying pressure of the second stage reaches the set requirement, the operation stops. At this time, the injection compressor needs to wait for about 5 minutes to run the protection before stopping.
6. Defrost
1 Determine the parameters of the chemical box program. Start the chemical box program after checking the error.
2 Observe whether the valve switches are correct during the phlegm process. Whether the water temperature and water quantity meet the requirements.
3 The pump should be running normally. There is no water leakage at each connection point.
7. Unloading
1 Start the cooling program and carry out the product array temperature. When the temperature drops to 15 °C, stop.
2 notify the sterile room to empty the discharge.
 

freeze dry machine technology is mainly used in:
(1) freeze-drying of biological products with poor thermal stability, biochemical products, blood products, genetic engineering products, etc.;
(2) To maintain the structure and activity of biological tissues, the treatment of biological tissues such as cortex, bone, cornea and heart valve for surgery; (3) Coffee to maintain food color, aroma, taste and nutrients, and to quickly rehydrate Freeze-drying of seasonings, meat, seafood, fruits and vegetables;
(4) Application in microcapsule preparation, drug controlled release materials, etc. Processing of health products such as ginseng, royal jelly, and turtles and Chinese herbal preparations to maintain the invariability of fresh substances;
(5) Ultrafine powder functional materials such as: optical fibers, superconducting materials, microwave dielectric materials, magnetic powders, and treatment of catalysts capable of accelerating reaction engineering.