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Lyophilizer
  • Lyophilizer
  • Lyophilizer
  • Lyophilizer
  • Lyophilizer

Lyophilizer

Product Category: Lyophilizer
Place of Origin: Made in China
Price: 1700-350000USD/
·Freeze area: 0.12m2
·Material plate size: Ф200mm
·Number of material trays: 4
·Material disc spacing: 70mm
· Cold trap temperature: ≤ -80 ° C (no load)
· Cold trap depth: 140mm
· Cold trap diameter: Ф215mm
  • Description
  • Attributes
  • Parameter
  • Range
  • Related users

  Lyophilizer are widely used in medical, pharmaceutical, biological research, chemical and food industries. The freeze-dried articles are easy to preserve for a long period of time. After adding water, they can return to their pre-lyophilized state and maintain their original biochemical characteristics. Huayu Brothers vacuum freeze-drying machine is suitable for laboratory use or small-scale production, and can meet the requirements of most labs for routine freeze-drying.
  What should I do if the power supply to the freeze dryer does not work? How does the freeze dryer not operate?
  Reason: There is no voltage or low voltage on the incoming line
  Countermeasures: Check the line power switch, fuse, and troubleshooting
  Reason: High voltage protection switch is disconnected
  Policy: Reset Cause: Loose wire
  Countermeasure: Check the wiring and tighten
  Cause: Compressor motor burned out
  Countermeasures: check, replace
  Cause: AC contactor is damaged
  Countermeasures: check, replace
  Reason: refrigerant leak in refrigeration dryer
  Countermeasures: Check leaks, leaks, and add refrigerants
  Reason: Automatic air switch is not turned on
  Countermeasure: Turn on the automatic air switch
  During the freeze-dryer process, the growth of microorganisms and the action of enzymes can not be carried out, so the original costume can be maintained. Since the drying is performed in a frozen state, the volume is almost constant, the original structure is maintained, and no condensation occurs. Since the drying is carried out under vacuum, there is very little oxygen, so some easily oxidized substances are protected. Freeze dryer drying can eliminate more than 95-99% of water, so that after drying products can be stored without deterioration. The dried material is loose and porous, and it is spongy. It dissolves quickly and completely after adding water, and it almost immediately restores its original properties. Lyophilizer operate at low temperatures and are therefore particularly suitable for many heat-sensitive materials. If proteins, microorganisms and the like do not degenerate or lose their vitality. Therefore, lyophilizer are widely used in medicine. When it is dried at low temperature, some volatile components in the material lose very little, which is suitable for some chemical products, drugs and foods.

Why to choose lyophilizer?
  Do you hope to have an equipment to dry fresh food material without nutrition lost, and meanwhile preserves its original taste, flavor and color? Only lyophilizer can meet this requirement. Do you want to get the most healthy dried food with the lowest cost far away from those outrageously expensive pharmaceutical freeze-dryers? Our lyophilizer can make it.
  Remarkable advantage of freeze-dried food:
  1, Retain biological activity
  To retain biological activity as much as possible, the material must be in low temperature environment, but on the contrary, drying needs heat involved. Heating will destroy biological activity and nutrition. Our solution is to get the liquid water in the material completely frozen to solid status. The water in the material is solid ice status during the whole heating processing till the material is completely dried. So, the biological activity is retained greatly.
  2, No damage to the nutrition
  Heating is no doubt the main reason of nutrition damage. By using our lyophilizer, heating processing occurs after material gets completely frozen to ice status. Thus, it typically retains 97% of the nutritional value.
  3, Taste, color and appearance
  Lyophilized by our lyophilizer, the material still tastes fresh, delicious as a snack, but a different try. The freeze dried material remains the same color, flavor and appearance as it was firstly harvested. And the volume of freeze dried material has no change, that is to say the appearance has no shrink or toughen. It is the real high quality preserved food.
  4, Longer shelf-life
  Freeze dried food material has a longer preservation time than frozen food, canned food and oven drying food. Having freeze dried food storage, you do not need to rack your brains what to eat and far away from pigmentum, additive, GMO and anti-season food material. Freeze-drying help us design a healthy lifestyle.

Application of our lyophilizer:
  Vacuum freeze-drying technology is applied to process food material to make freeze dried food. The lyophilizer is used in all conceivable kinds of agricultural products with top drying quality.
  Fruits: durian, strawberry, mango, apricot, kiwifruit, pineapple, lemon, raspberry, avocado, banana etc.
  Vegetables: broccoli, parsley, mushroom, bean, scallion, asparagus, onion, celery, carrot, tomato, pepper etc.
  Other food: beef, coffee, colostrums, herbal, flower, tea, honey, sea food and all kinds of pets food.
  Working principle:
  In a sealed vacuum surrounding, by heating the complete frozen food material, the moisture in the frozen material will be evaporated to a continuous frozen vapor condenser. After 20-30 hours, the food material is dried, the water is moved to vapor condenser of the lyophilizer.
  Construction and main components of lyophilizer:
  Each single lyophilizer is composed by a vessel/chamber with shelf plates, trays and vapor condensers inside. The vessel can be cylinder shaped or cuboid shaped.
  All-in-one: for small lyophilizer, all components can be mounted on one frame. It is easy to install and ship.
  Assemble: for big lyophilizer, vessel is one individual module, refrigerator is a module, vacuum pump is a module, heating system is a module, and control system is another module. We will get all modules collected on customer's site.
  1, Vessel, shelf plates, trays and vapor condenser:
  Shelf plates and trays can be stainless steel or aluminum, vapor condenser is made of stainless steel. The standard configuration of stainless steel is SUS304, we have SUS316 for option. The standard configuration of shelf plate is welded pieces; we have whole pieces for option.
  2, Refrigerator:
  Brand: Refcomp, Bitzer, Carrier, Frascold, Hanbell, Fusheng, and Chinese local brands for your option.
  The refrigeration system freezes the shelf plates during in-place freezing, evacuation and the early stages of drying. It also freezes the vapour condenser during the drying cycle. Screw type of compressor is adopted on the large scaled lyophilizer and piston for small ones, and the refrigerant used is R404A, R507 etc environment friendly Freon.
  3, Vacuum pump
  Brand: Tuthill, Edwards, Leybold, Ulvac, Diavac and Chinese local brands for your option.
  The vacuum system is composed of drying chamber, condenser, vacuum pipes, valves, back pump and holding pump. It requires no leaks; Vacuum system is an essential for the rapid sublimation. Backing pumps and holding pumps are required for large scaled lyophilizer to give efficient capacity for evacuation.
  4, Heating system
  The heat-plates are cooled or heated with a heat transfer fluid. This fluid can be chilled or heated to provide in-place freezing or heating of the product during the drying cycle. An electric boiler directly heats the fluid, and chilling is through an intermediate heat exchanger. A centrifugal pump provides the forced circulation of the heat transfer fluid. Optional fluid: ethanol, glycol, silicon oil, deicing fluid, alcohol, water etc.
  5, Defrost system
  Water is used for defrosting the vapour condenser. As an optional extra, heat can be reclaimed from the refrigeration compressor to enable 60C hot water defrost, greatly reducing defrosting times over conventional cold water.
  6, Control system
  Brand: Siemens or Advantech or local brand for option.
  CE, UL approved Siemens or Advantech PLC is adopted for control system. All electrical components are compatible with local supplies including voltage, frequency, wire, motor circuit breakers and overload protection. A variety of sensors support the data acquisition and control of lyophilizer: Pressure transducers are fitted, which monitor and control the refrigeration system. Vacuum pressure is monitored at the product chamber. Temperature sensors measure and control the heating fluid.

  Installation and training:
  We have engineers with 10 years installation experience available for our lyophilizer installation guidance and service; and train customer's workers operate the machine.
  Packing and delivery
  Small lyophilizer normally packed by wooden box and shipped by standard container. If export to European countries or north America countries, the wooden box will be fumigated. As the chamber of lyophilizer FD-500-FD2500 is too big, the vessel is shipped by FR container or bulk vessel, the rest normally packed by wooden box and shipped by standard container.

Why to choose lyophilizer?
  Do you hope to have an equipment to dry fresh food material without nutrition lost, and meanwhile preserves its original taste, flavor and color? Only lyophilizer can meet this requirement. Do you want to get the most healthy dried food with the lowest cost far away from those outrageously expensive pharmaceutical freeze-dryers? Our lyophilizer can make it.
  Remarkable advantage of freeze-dried food:
  1, Retain biological activity
  To retain biological activity as much as possible, the material must be in low temperature environment, but on the contrary, drying needs heat involved. Heating will destroy biological activity and nutrition. Our solution is to get the liquid water in the material completely frozen to solid status. The water in the material is solid ice status during the whole heating processing till the material is completely dried. So, the biological activity is retained greatly.
  2, No damage to the nutrition
  Heating is no doubt the main reason of nutrition damage. By using our lyophilizer, heating processing occurs after material gets completely frozen to ice status. Thus, it typically retains 97% of the nutritional value.
  3, Taste, color and appearance
  Lyophilized by our lyophilizer, the material still tastes fresh, delicious as a snack, but a different try. The freeze dried material remains the same color, flavor and appearance as it was firstly harvested. And the volume of freeze dried material has no change, that is to say the appearance has no shrink or toughen. It is the real high quality preserved food.
  4, Longer shelf-life
  Freeze dried food material has a longer preservation time than frozen food, canned food and oven drying food. Having freeze dried food storage, you do not need to rack your brains what to eat and far away from pigmentum, additive, GMO and anti-season food material. Freeze-drying help us design a healthy lifestyle.

Application of our lyophilizer:
  Vacuum freeze-drying technology is applied to process food material to make freeze dried food. The lyophilizer is used in all conceivable kinds of agricultural products with top drying quality.
  Fruits: durian, strawberry, mango, apricot, kiwifruit, pineapple, lemon, raspberry, avocado, banana etc.
  Vegetables: broccoli, parsley, mushroom, bean, scallion, asparagus, onion, celery, carrot, tomato, pepper etc.
  Other food: beef, coffee, colostrums, herbal, flower, tea, honey, sea food and all kinds of pets food.
  Working principle:
  In a sealed vacuum surrounding, by heating the complete frozen food material, the moisture in the frozen material will be evaporated to a continuous frozen vapor condenser. After 20-30 hours, the food material is dried, the water is moved to vapor condenser of the lyophilizer.
  Construction and main components of lyophilizer:
  Each single lyophilizer is composed by a vessel/chamber with shelf plates, trays and vapor condensers inside. The vessel can be cylinder shaped or cuboid shaped.
  All-in-one: for small lyophilizer, all components can be mounted on one frame. It is easy to install and ship.
  Assemble: for big lyophilizer, vessel is one individual module, refrigerator is a module, vacuum pump is a module, heating system is a module, and control system is another module. We will get all modules collected on customer's site.
  1, Vessel, shelf plates, trays and vapor condenser:
  Shelf plates and trays can be stainless steel or aluminum, vapor condenser is made of stainless steel. The standard configuration of stainless steel is SUS304, we have SUS316 for option. The standard configuration of shelf plate is welded pieces; we have whole pieces for option.
  2, Refrigerator:
  Brand: Refcomp, Bitzer, Carrier, Frascold, Hanbell, Fusheng, and Chinese local brands for your option.
  The refrigeration system freezes the shelf plates during in-place freezing, evacuation and the early stages of drying. It also freezes the vapour condenser during the drying cycle. Screw type of compressor is adopted on the large scaled lyophilizer and piston for small ones, and the refrigerant used is R404A, R507 etc environment friendly Freon.
  3, Vacuum pump
  Brand: Tuthill, Edwards, Leybold, Ulvac, Diavac and Chinese local brands for your option.
  The vacuum system is composed of drying chamber, condenser, vacuum pipes, valves, back pump and holding pump. It requires no leaks; Vacuum system is an essential for the rapid sublimation. Backing pumps and holding pumps are required for large scaled lyophilizer to give efficient capacity for evacuation.
  4, Heating system
  The heat-plates are cooled or heated with a heat transfer fluid. This fluid can be chilled or heated to provide in-place freezing or heating of the product during the drying cycle. An electric boiler directly heats the fluid, and chilling is through an intermediate heat exchanger. A centrifugal pump provides the forced circulation of the heat transfer fluid. Optional fluid: ethanol, glycol, silicon oil, deicing fluid, alcohol, water etc.
  5, Defrost system
  Water is used for defrosting the vapour condenser. As an optional extra, heat can be reclaimed from the refrigeration compressor to enable 60C hot water defrost, greatly reducing defrosting times over conventional cold water.
  6, Control system
  Brand: Siemens or Advantech or local brand for option.
  CE, UL approved Siemens or Advantech PLC is adopted for control system. All electrical components are compatible with local supplies including voltage, frequency, wire, motor circuit breakers and overload protection. A variety of sensors support the data acquisition and control of lyophilizer: Pressure transducers are fitted, which monitor and control the refrigeration system. Vacuum pressure is monitored at the product chamber. Temperature sensors measure and control the heating fluid.

  Installation and training:
  We have engineers with 10 years installation experience available for our lyophilizer installation guidance and service; and train customer's workers operate the machine.
  Packing and delivery
  Small lyophilizer normally packed by wooden box and shipped by standard container. If export to European countries or north America countries, the wooden box will be fumigated. As the chamber of lyophilizer FD-500-FD2500 is too big, the vessel is shipped by FR container or bulk vessel, the rest normally packed by wooden box and shipped by standard container.

Freeze-drying machines are now widely used in biopharmaceuticals, Chinese herbal medicines, blood products, biological products, pharmaceuticals and active substances, especially in the pharmaceutical industry. It is a drying method for pre-freezing the material below the eutectic point temperature and removing the moisture in the material through a sublimation process under a certain vacuum state. The unit is mainly composed of three major operating systems of refrigeration, heating and vacuum.

Related users (part)
Tsinghua University Peking University Huazhong Agricultural University
Beihang University, Chinese Academy of Medical Sciences, Nanjing University of Science and Technology
Beijing University of Science and Technology China Agricultural University South China University of Technology
Beijing Institute of Technology Nanjing University of Technology Xi'an University of Technology
Sichuan University Hunan University Qiqihar University
Tianjin University Lanzhou University Xiamen University
Tongji University Nanjing University Shenyang Pharmaceutical University
Zhejiang Sci-Tech University Zhongshan University Wuhan University
Zhejiang University Hunan University of Science and Technology Wuhan University of Technology
University of Science and Technology of China, Guangdong Ocean University Hubei Hong Pharmaceutical Co., Ltd.
Civil Aviation University of China Shenyang University of Technology Institute of Process Engineering, Chinese Academy of Sciences
Huazhong University of Science and Technology Beijing Orchard Research Institute Changsha Qixi New Material Technology Co., Ltd.
Beijing University of Chemical Technology Shandong Daguan Pharmaceutical Technology Co., Ltd. Dongguan City Original Ecological Biotechnology Co., Ltd.
Guizhou Institute of Biotechnology Sanming Hezhong Biotechnology Co., Ltd Harbin Children's Pharmaceutical Factory
National University of Defense Technology Changchun Hengchen Biotechnology Co., Ltd. Jinan Hengjian Pharmaceutical Technology Co., Ltd.
Institute of Chemistry, Chinese Academy of Sciences Dongguan Lujian Biotechnology Co., Ltd. Institute of Materia Medica, Chinese Academy of Medical Sciences
South China Sea Fisheries Research Institute Shanghai Institute of Materia Medica, Chinese Academy of Sciences Jiangsu Ouwei Pharmaceutical Co., Ltd.
Ministry of Agriculture Planning and Design Institute Shenzhen Jianyuan Pharmaceutical Technology Co., Ltd. Hangzhou Baicheng Pharmaceutical Technology Co., Ltd.
China Institute of Metrology Science Dongguan Sanwei Biotechnology Co., Ltd. Fujian Institute of Research on the Structure of Matter, Chinese Academy of Sciences
Liaoning Wanjia Pharmaceutical Technology Co., Ltd. Suzhou Global Chromatography Co., Ltd. China Food and Drug Testing Institute Food Institute

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Address:C706 Changyin Building, NO.88 Yongding Road, Haidian District, Beijing, China
Hotline:+86-13161061291
Email:sales@bjsyhx.com.cn Facebook:SYHXfreezedryer
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