Six elements of the laboratory to purchase a small freeze dryer

Six elements of the laboratory to purchase a small freeze dryer
Laboratory small-scale freeze dryers, also known as laboratory vacuum freeze dryers, small freeze dryers, when purchasing, not only must consider the price but also its applicability, the six elements of small freeze dryer purchase, Beijing Songyuan freeze dryer manufacturers are summarized as follows:
1. The manufacturer's choice.
The preferred strength brand, and has many years of professional production of freeze dryer experience and professional technology freeze dryer manufacturers.
2. Cold trap temperature.
A cold trap is a device for trapping steam between a freeze-drying chamber and a vacuum pump. The lower the cold trap temperature, the stronger the trap capability of the cold trap, but the lower the cold trap temperature, the higher the cooling requirements, and the higher the machine cost and operating cost.
The cold trap temperature of Beijing Songyuan Laboratory freeze dryer mainly has three grades of -50 °C, -60 °C, and -80 °C. The lyophilizer with a cold trap temperature of -50 °C is suitable for lyophilization of water solvent or solvent freezing point above -40 °C. The effect of cold trap temperature on water trapping capacity indicates that the temperature of the cold trap drops from -35 °C to -50. °C, the water catching capacity is obviously improved, the cold trap temperature is lower than -50 °C, and the water trap capacity of the cold trap is not significantly improved. Therefore, in the absence of special needs, the cold trap temperature of -50 °C can be selected. The lyophilizer with a cold trap temperature of around -80 °C is suitable for lyophilization of most products such as organic solvents, as well as lyophilization of some special products.
3. The amount of ice.
It refers to the amount of steam that can be trapped by a cold trap, and is related to the total amount of water or other solvent sublimation in the laboratory's daily experimental operation. The cold trap ice of the laboratory freeze dryer has 3kg and 6kg, which is suitable for various experimental requirements.
4, the ultimate vacuum
The ultimate vacuum reflects the leakage of the freeze dryer and the pumping efficiency of the vacuum pump. The vacuum degree of the experimental operation should be within a reasonable range, the degree of vacuum is too high, which is not conducive to heat transfer, and the drying speed is rather decreased.
5, control display system
The laboratory series of freeze dryers are mainly used for lyophilization of materials, small batch production and freeze-drying process conditions. The control system shall have real-time display parameters of freeze-drying process, such as cold trap temperature, vacuum degree, phase time and total process time; set, modify and effectively execute the freeze-drying process program;
6, freeze-drying methods and functions.
Depending on the sample, there are different options for lyophilization. The common laboratory freeze-drying experiments adopt the Process B method, that is, freeze-drying in the freeze-drying chamber or freeze-drying in the hanging bottle. If the freeze-dried chamber is freeze-dried, you need to purchase the freeze-drying chamber, and you need to do the freeze-drying of the vial. Also choose the capping device; if it is lyophilized, choose multi-manifold, suitable for round bottom flask, wide-mouth filter bottle or ampoule, but pay attention to whether you need to select the corresponding adapter to use; if the user The samples involved in the test can be lyophilized in the chamber or lyophilized in the external bottle.
Different experiments and different samples have different functional requirements for the freeze dryer. Generally speaking, it is generally recommended to use a shelf type freeze dryer for freeze-drying of food, Chinese herbal medicine, powder materials, etc., and for the operation of the vial, it is necessary to select Freeze-dried machine with gland device; freeze-dried preservation of microbial strains is recommended to use bottle-hanging type and must be selected for ampoules adapter to freeze-dry; if you want to study freeze-drying process curve, you must choose controller to support eutectic Point test equipment and software work models... The purpose of the selection is to configure according to specific needs.