What is the control system of industrial vacuum freeze dryer?
The control system of industrial vacuum freeze dryer is the command mechanism of the whole machine. The control of vacuum freeze-drying includes the start and stop of refrigerators, vacuum pumps and circulating pumps, the control of heating power, the test and control of temperature, vacuum and time, automatic protection and alarm devices, etc. Depending on the degree of automation required, the control requirements are also different, and can be divided into four categories: manual control (ie, button control), semi-automatic control, full-automatic control, and microcomputer control.
On industrial vacuum freeze dryer equipment, people often have to start refrigerators, vacuum systems, open or close various control valves, or make the pressure in the vacuum chamber operate according to certain requirements. This is the so-called industrial vacuum. Freeze dryer control.
The requirements for the control system of the vacuum freeze-drying process, using manual and automatic methods to achieve the entire freeze-drying process of the industrial vacuum freeze-dryer and automatic stoppering and automatic decontamination control. The specific requirements are:
(1) The lyophilized curve value can be stored in the disk, and real-time display and historical data display can be performed on the computer screen, and instant printing is supported. These curves include:
A: material temperature curve; B: plate temperature curve; C: water vapor condenser curve; D: vacuum degree curve;
(2) Measurement error of control system: temperature + 1.0 ℃, vacuum degree + 10Pa. Product final moisture content + 1%
(3) The system can set or modify the freeze-drying curve of medicines according to different products. During the freeze-drying process, the material can be tracked and adjusted by adjusting the temperature of the heating plate, the heat supply, the vacuum of the cabinet, and the temperature of the water condenser. curve;
(4) Set the temperature of the water vapor condenser. Track the set temperature by controlling the refrigerator energy regulator;
(5) The vacuum degree in the box can be set, and the required vacuum degree can be adjusted through the micro-movement valve;
6 (6) Fault alarm and handling, including alarm of vacuum unit starting pressure, alarm of vacuum degree exceeding set value during freeze-drying and related data display;
7 (7) Automatic stoppering of medicines: automatic stoppering and sealing treatment before the medicines and biological products are out of the box to ensure the cleanliness and frozen state of the products and improve the quality of frozen products
(8) Disinfection between mass production before and after: in order to prevent cross-contamination, automatic in-situ disinfection between two mass productions. Requires GMP compliance.