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Your Location: Home >> News >> Enterprise dynamics >> Classification and selection of freeze dryers

Classification and selection of freeze dryers

Release Date: 2019/7/19 17:39:26 .
Browse: 1682

Classification and selection of freeze dryers
The complete freeze dryer is a complex device that integrates functions such as fast, cool, heat drying, control, in-place cleaning and disinfection.
The freeze dryer can be classified in different ways.
According to the object, it can be divided into food freeze dryer and drug freeze dryer;
According to the processing capacity, it can be divided into large, medium and small freeze dryers;
According to the application, it can be divided into test, pilot test (product intermediate test, freeze-drying process can be used with large-scale production) and production freeze dryer.
The test freeze dryer is mainly used to explore and study the freeze-drying characteristics of new materials; to explore and determine the process parameters of the new material freeze-drying process.
Including: studying the problems that may occur during the freeze-drying process of new materials;
Study the effects of various parameters on the freeze-drying of new materials;
Explore the cooling rate and pre-freezing temperature of the pre-freezing process, the type and concentration of the protective agent, the primary and secondary drying process parameters and control methods. In the hope of reaching
It can not only obtain high quality freeze-dried products, but also reduce the time and energy consumption of the freeze-drying process.
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Such freeze dryers are typically pre-frozen in other cryocontainers and a small amount can be carried out in a cold trap.
The drying chamber is a transparent bell jar with a built-in stainless steel sample rack.
The freeze dryer has a simple structure and a single control function, and is generally suitable for lyophilization of simple water-soluble samples.
Process: Pre-freezing is done outside the dry room (either external or cold trap) and then moved to the drying chamber shelf before the vacuum pump can be turned on.
Disadvantages: Separation of pre-freezing and drying. Refrigeration will no longer continue to be supplied to the sample during the drying phase, and the temperature of the material will rise significantly as the external heat is introduced. If material
Temperatures above their glass transition temperature or eutectic point temperature will cause the material to collapse or melt, which will have a large impact on the quality of the lyophilized product.
In order to solve this problem, Shuangjia specially launched the SJIA-5FE freeze dryer for small freeze dryers.
The pilot freeze dryer is mainly used in various medical and food research institutions for the process exploration before mass production. Generally speaking,
The process curve obtained on the pilot freeze dryer can be directly applied to the production freeze dryer, and then the process parameters are slightly adjusted according to the operation.

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