Welcome to visit Beijing Songyuan Huaxing official website!
E-mail: sales@bjsyhx.com.cn
Product List
Breaking News
What are the advantages of a laboratory freeze dryer used in a laboratory over conventional methods?
The laboratory freeze dryer uses the physical principle to freeze the moisture in the compressed air to below the dew point, so that it can be precipitated from the air....
Analysis on the drying principle of freeze dryer
I believe everyone is familiar with freeze dryers. Such a machine that integrates freezing and drying has been favored by most experiments. The principle of freeze drying of freeze dryers is actually not complicated. Freezing and drying are divided into two processes. ...
How to properly maintain an industrial vacuum freeze dryer?
Industrial vacuum freeze dryer is composed of refrigeration system, vacuum system, heating system, electrical instrument control system. ...
What is the control system of industrial vacuum freeze dryer?
The control system of industrial vacuum freeze dryer is the command mechanism of the whole machine....
Analysis of periodic inspection and maintenance methods of pilot freeze dryer
Repair and eliminate the leakage and failure of the refrigeration system, vacuum system and heating system, and check whether the indicators of the pilot freeze dryer are in a normal state;...
Contact Us
Beijing Songyuan Huaxing
Service Line:+86-13161061291
Song Yuan:+86-13161061291
Address:C706 Changyin Building, NO.88 Yongding Road, Haidian District, Beijing, China
Email:sales@bjsyhx.com.cn
Facebook:SYHXfreezedryer
Your Location: Home >> Application >> User case >> Effect of material tray on the quality of medicinal freeze dryer products

Effect of material tray on the quality of medicinal freeze dryer products

Release Date: Wednesday 4 . 2019
Browse: 341

Effect of material tray on the quality of medicinal freeze dryer products
The medicinal freeze-drying machine is also called a pharmaceutical freeze-drying machine, and is characterized in that the products are generally completed in the whole process of pre-freezing, heat preservation and sublimation drying on a set of shelves in the same drying box. Since the same set of shelves has both refrigeration and heating, it is generally indirectly conducted by intermediate media. The uneven temperature of the shelf and the poor heat conduction of the tray lead to high energy consumption, long process, and no product design. Problems such as residual water content standards are a key factor in the long-term development of pharmaceutical companies.
The lyophilizer generally puts the raw materials in a tray placed on the shelf in a tray for freezing, sublimation drying, analytical drying, and the thickness of the tray should be considered to be cold and hot deformation, so it should not be too thin, generally 1.5 mm. Left and right, the vials or foods containing the medicines are placed in the tray at a height of about 10-15 Mm, and the temperature is transmitted from the hot and cold temperature of the shelf to the bottom of the tray until the upper end of the zui is frozen, sublimated and dried, and the dried articles are analyzed. However, since the vials, medicines, biological products or foods containing the medicines are contained in the trays at a height of about 10-15 mm, the temperature transfer takes a long time, and because the shelf temperature is not uniform, the moisture content of the freeze-dried products is not Uniformity, the yield of product residual moisture is affected.
The trays on the shelves are made of stainless steel, which are deformed by thermal expansion and contraction for a long time during lyophilization. Therefore, various manufacturers have spent a lot of manpower and financial resources, such as the flatness and surface of the surface of the shelf. The position of the solder joint, the thermal expansion and contraction caused by the intermittent welding and the material, etc., various problems will directly affect the heat transfer performance between the shelf and the product and the tray, which may cause temperature unevenness. Therefore, there are often some The residual moisture content in the freeze-dried vials reflected by the user is inconsistent, and some of them have a large difference, and the product design residual water content standard has not been reached. Some users use a drawer type tray box or a bulk vial when lyophilizing the vial, which wastes the loading and unloading time, and is easily damaged when loading and unloading the medicine bottle. Now, foreign countries have begun to apply the tray for forming a sterile film but the price High, easy to damage, long-term use and other defects.

share to:
Songyuan Freeze Dryer logo
Address:C706 Changyin Building, NO.88 Yongding Road, Haidian District, Beijing, China
Hotline:+86-13161061291
Email:sales@bjsyhx.com.cn Facebook:SYHXfreezedryer
Fax:+86-10-58895379