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In-situ freeze dryers
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  • In-situ freeze dryers
  • In-situ freeze dryers
  • In-situ freeze dryers

In-situ freeze dryers

Product Category: Freeze Dryer
Beijing Songyuan Huaxing Technology Development Co., Ltd. specializes in in-situ freeze dryers, which has 20+ years of industry experience. To reduce equipment energy consumption, branches and special maintenance stations are set up throughout the country.
Place of Origin: Made in China
Price: 1700-350000USD/set
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As we all know, the history of in-situ freeze dryers is different because of the different industrialization process of manufacturing, which also results in the diversified development characteristics of in-situ freeze dryer equipment, and the development of China's packaging machinery industry starts. Late, but because of its huge market potential, its rapid development has gradually become a big country in the packaging machine industry, and it is also developing internationally. The EU countries have also become a market with many exchanges with China in the packaging machine industry.

In today's society, the sale of various in-situ freeze dryers is very influential, and in-situ freeze dryers are receiving more and more attention. The drying equipment industry is facing an unprecedented development. In-situ freeze dryers bring greater opportunities and battles.
The in-situ freeze dryer uses freeze-drying technology to perform low-temperature drying on heat sensitive substances such as antibiotics, vaccines, blood products, enzyme hormones and other biological tissues under vacuum conditions. In-situ freeze dryers are widely used in pharmaceuticals, biological products, chemicals and The food industry, freeze-drying technology is very suitable. In-situ freeze dryers are suitable for laboratory use or small quantities. In-situ freeze dryer technology has a wide range of applications in the fields of bioengineering, pharmaceutical industry, food industry, materials science and deep processing of agricultural and sideline products. So what are the advantages of in-situ freeze dryer drying technology:
1. In the process of in-situ freeze dryer, the growth of microorganisms and the action of enzymes cannot be carried out, so the original sex can be maintained. Since the drying is carried out in a frozen state, the volume is almost constant, the original structure is maintained, and concentration does not occur.
2. Since the drying is carried out under vacuum, there is very little oxygen, so some easily oxidizable substances are protected.
3, drying can exclude more than 95-99% of water, in-situ freeze dryer to make the product can be preserved for a long time without deterioration.
4. The dried material is porous and spongy. After adding water, it dissolves quickly and completely, and immediately restores the original trait.
5. In-situ freeze dryers are carried out at low temperatures and are therefore particularly suitable for many heat sensitive materials. Such as protein, microorganisms and the like will not degenerate or lose biological vitality. In-situ freeze dryers are therefore widely used in medicine.
6. When drying at low temperature, some volatile components in the material are lost little, suitable for some chemical products, medicines and foods to be dry.

The in-situ freeze dryer consists of a drying oven, a vacuum system, a refrigeration system, a cold trap system, a heating system, a capping system, and an automatic control system. In addition, large-scale pharmaceutical freeze dryers often include a steam sterilization system (SIP) and a in-situ cleaning system (CIP).
The application of the in-situ freeze dryer in the pharmaceutical powder injection reagent avoids the decomposition of the medicine powder needle due to high heat, and avoids the slow compatibility change between the medicines. The medicine is accurately measured and the appearance is excellent, which is beneficial to increase the stability of the medicine and facilitate the medicine. Long-term storage. In-situ freeze dryer is widely used in the preparation of freeze-dried powder injections of ligustrazine phosphate, sodium ozagrel, L-carnitine, omeprazole and other drugs.
The in-situ freeze-drying machine is used to prepare the lyophilized powder injection. The conventional steps are as follows: 40%~90% of the prescribed amount of water for injection is cooled to 20 ° C ~ 60 ° C, adjust or not adjust the pH, sequentially add the local substances, stir, measure PH Or adjust PH, hydration, temperature control conditions, add prescription amount of activated carbon, stirring decolorization, pressure filtration, filter sterilization to obtain sterile liquid, dispense it into vials, freeze-dry, cover, freeze-dry Powder injection. The in-situ freeze dryer is simple in operation and short in production cycle, and is suitable for industrial production.
The powdered needle preparation after freeze-drying has the problems of low bioavailability and slow drug effect of traditional oral solid preparations. The freeze-dried powder needle does not contain organic solvents in water needles, and has good stability and does not require high temperature. Advantages such as sterilization.
in-situ freeze dryer technology is mainly used in:
(1) freeze-drying of biological products with poor thermal stability, biochemical products, blood products, genetic engineering products, etc.;
(2) To maintain the structure and activity of biological tissues, the treatment of biological tissues such as cortex, bone, cornea and heart valve for surgery; (3) Coffee to maintain food color, aroma, taste and nutrients, and to quickly rehydrate Freeze-drying of seasonings, meat, seafood, fruits and vegetables;
(4) Application in microcapsule preparation, drug controlled release materials, etc. Processing of health products such as ginseng, royal jelly, and turtles and Chinese herbal preparations to maintain the invariability of fresh substances;
(5) Ultrafine powder functional materials such as: optical fibers, superconducting materials, microwave dielectric materials, magnetic powders, and treatment of catalysts capable of accelerating reaction engineering.

In today's society, the sale of various in-situ freeze dryers is very influential, and in-situ freeze dryers are receiving more and more attention. The drying equipment industry is facing an unprecedented development. In-situ freeze dryers bring greater opportunities and battles.
The in-situ freeze dryer uses freeze-drying technology to perform low-temperature drying on heat sensitive substances such as antibiotics, vaccines, blood products, enzyme hormones and other biological tissues under vacuum conditions. In-situ freeze dryers are widely used in pharmaceuticals, biological products, chemicals and The food industry, freeze-drying technology is very suitable. In-situ freeze dryers are suitable for laboratory use or small quantities. In-situ freeze dryer technology has a wide range of applications in the fields of bioengineering, pharmaceutical industry, food industry, materials science and deep processing of agricultural and sideline products. So what are the advantages of in-situ freeze dryer drying technology:
1. In the process of in-situ freeze dryer, the growth of microorganisms and the action of enzymes cannot be carried out, so the original sex can be maintained. Since the drying is carried out in a frozen state, the volume is almost constant, the original structure is maintained, and concentration does not occur.
2. Since the drying is carried out under vacuum, there is very little oxygen, so some easily oxidizable substances are protected.
3, drying can exclude more than 95-99% of water, in-situ freeze dryer to make the product can be preserved for a long time without deterioration.
4. The dried material is porous and spongy. After adding water, it dissolves quickly and completely, and immediately restores the original trait.
5. In-situ freeze dryers are carried out at low temperatures and are therefore particularly suitable for many heat sensitive materials. Such as protein, microorganisms and the like will not degenerate or lose biological vitality. In-situ freeze dryers are therefore widely used in medicine.
6. When drying at low temperature, some volatile components in the material are lost little, suitable for some chemical products, medicines and foods to be dry.

The in-situ freeze dryer consists of a drying oven, a vacuum system, a refrigeration system, a cold trap system, a heating system, a capping system, and an automatic control system. In addition, large-scale pharmaceutical freeze dryers often include a steam sterilization system (SIP) and a in-situ cleaning system (CIP).
The application of the in-situ freeze dryer in the pharmaceutical powder injection reagent avoids the decomposition of the medicine powder needle due to high heat, and avoids the slow compatibility change between the medicines. The medicine is accurately measured and the appearance is excellent, which is beneficial to increase the stability of the medicine and facilitate the medicine. Long-term storage. In-situ freeze dryer is widely used in the preparation of freeze-dried powder injections of ligustrazine phosphate, sodium ozagrel, L-carnitine, omeprazole and other drugs.
The in-situ freeze-drying machine is used to prepare the lyophilized powder injection. The conventional steps are as follows: 40%~90% of the prescribed amount of water for injection is cooled to 20 ° C ~ 60 ° C, adjust or not adjust the pH, sequentially add the local substances, stir, measure PH Or adjust PH, hydration, temperature control conditions, add prescription amount of activated carbon, stirring decolorization, pressure filtration, filter sterilization to obtain sterile liquid, dispense it into vials, freeze-dry, cover, freeze-dry Powder injection. The in-situ freeze dryer is simple in operation and short in production cycle, and is suitable for industrial production.
The powdered needle preparation after freeze-drying has the problems of low bioavailability and slow drug effect of traditional oral solid preparations. The freeze-dried powder needle does not contain organic solvents in water needles, and has good stability and does not require high temperature. Advantages such as sterilization.
 

in-situ freeze dryer technology is mainly used in:
(1) freeze-drying of biological products with poor thermal stability, biochemical products, blood products, genetic engineering products, etc.;
(2) To maintain the structure and activity of biological tissues, the treatment of biological tissues such as cortex, bone, cornea and heart valve for surgery; (3) Coffee to maintain food color, aroma, taste and nutrients, and to quickly rehydrate Freeze-drying of seasonings, meat, seafood, fruits and vegetables;
(4) Application in microcapsule preparation, drug controlled release materials, etc. Processing of health products such as ginseng, royal jelly, and turtles and Chinese herbal preparations to maintain the invariability of fresh substances;
(5) Ultrafine powder functional materials such as: optical fibers, superconducting materials, microwave dielectric materials, magnetic powders, and treatment of catalysts capable of accelerating reaction engineering.

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Address:C706 Changyin Building, NO.88 Yongding Road, Haidian District, Beijing, China
Hotline:+86-13161061539
Email:service@bjsyhx.com.cn Facebook:SYHXfreezedryer
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